研究業績

原著論文  (equal contribution, * corresponding author)

  1. Tomoyuki Masuda*†, Kazuhiro Ishii†, Yukio Morishita, Nobuaki Iwasaki, Yasuyuki Shibata, Akira Tamaoka. Hepatic histopathological changes and dysfunction in primates following exposure to organic arsenic diphenylarsinic acid. The Journal of Toxicological Sciences 43 (5), 291- 298, 2018.(組織病理学・毒性病理組織学・サル)
    https://www.jstage.jst.go.jp/article/jts/43/5/43_291/_article
  2. 増田知之*,小関美咲,邵宇晨,加藤隼平,山中敏正.自撮り写真の目にどれだけ盛れば魅力が下がるのか―「盛る」感性の性差・地域差の検討―.情報処理学会研究報告エンタテインメントコンピューティング (EC), 2018-EC-47 (9), 1-5, 2018.(感性工学・サブカルチャー・盛り)
    https://tsukuba.repo.nii.ac.jp/?action=pages_view_main&active_action=repository_view_main_item_detail&item_id=45795&item_no=1&page_id=13&block_id=83
  3. Tomoyuki Masuda*, Kazuhiro Ishii*, Tomohiro Nakayama, Nobuaki Iwasaki, Yasuyuki Shibata, Akira Tamaoka. High-sensitivity quantitative analysis reveals the non-linear relationship between the dose and deposition of diphenylarsinic acid in the rat central nervous system following its subchronic exposure. Neurotoxicology and Teratology 65, 26-33, 2018.(神経毒性学・ラット)
    https://tsukuba.repo.nii.ac.jp/?action=pages_view_main&active_action=repository_view_main_item_detail&item_id=45803&item_no=1&page_id=13&block_id=83
  4. Tomoyuki Masuda, Kazuhiro Ishii*, Yasuo Seto, Tomoko Hosoya, Ryuta Tanaka, Tomohiro Nakayama, Nobuaki Iwasaki, Yasuyuki Shibata, Akira Tamaoka. Long-term accumulation of diphenylarsinic acid in the central nervous system of cynomolgus monkeys. Archives of Toxicology 91 (8), 2799-2812, 2017.(神経毒性学・サル)
    https://link.springer.com/article/10.1007/s00204-016-1928-z
  5. Yuko Yoshimura, Chihiro Ishikawa, Haruki Kasegai, Tomoyuki Masuda, Masaaki Yoshikawa, Takashi Shiga. Roles of 5-HT1A receptor in the expression of AMPA receptor and BDNF in developing mouse cortical neurons. Neuroscience Research 115, 13-20, 2017.(神経科学)
    https://tsukuba.repo.nii.ac.jp/?action=pages_view_main&active_action=repository_view_main_item_detail&item_id=41361&item_no=1&page_id=13&block_id=83
  6. Tomoyuki Masuda†, Junko Itoh†, Takuya Koide†, Yasushi Tomidokoro, Yosuke Takei, Kazuhiro Ishii*, Akira Tamaoka. Transforming growth factor-β1 in the cerebrospinal fluid of patients with distinct neurodegenerative diseases. Journal of Clinical Neuroscience 35, 47-49, 2017.(神経内科学・神経変性疾患)
    https://tsukuba.repo.nii.ac.jp/?action=pages_view_main&active_action=repository_view_main_item_detail&item_id=46014&item_no=1&page_id=13&block_id=83
  7. Sittiphan Jiyavorananda, Hiroko Ishikawa, Shunsuke Sakai, Katsuo Yamanaka, Toshimasa Yamanaka, Tomoyuki Masuda*. Elucidation of factors predicting the impression of “Yuru-sa” in Japanese Yuru-kyara mascot characters. International Journal of Affective Engineering 15 (3), 231-238, 2016.(感性工学・サブカルチャー・ゆるキャラ)
    https://tsukuba.repo.nii.ac.jp/?action=pages_view_main&active_action=repository_view_main_item_detail&item_id=45825&item_no=1&page_id=13&block_id=83
  8. Masaaki Yoshikawa, Tomoyuki Masuda, Azusa Kobayashi, Kouji Senzaki, Shigeru Ozaki, Shin Aizawa, Takashi Shiga. Runx1 contributes to the functional switching of bone morphogenetic protein 4 (BMP4) from neurite outgrowth promoting to suppressing in dorsal root ganglion. Molecular and Cellular Neuroscience 72, 114-122, 2016.(神経科学)
    https://www.sciencedirect.com/science/article/pii/S1044743116300148?via%3Dihub
  9. Yuuki Ogihara†, Tomoyuki Masuda†*, Shigeru Ozaki, Masaaki Yoshikawa, Takashi Shiga. Runx3-regulated expression of two Ntrk3 transcript variants in dorsal root ganglion neurons. Developmental Neurobiology 76 (3), 313-322, 2016.(神経科学)
    https://tsukuba.repo.nii.ac.jp/?action=pages_view_main&active_action=repository_view_main_item_detail&item_id=46285&item_no=1&page_id=13&block_id=83
  10. Masaaki Yoshikawa, Mizuki Hirabayashi, Ryota Ito, Shigeru Ozaki, Shin Aizawa, Tomoyuki Masuda, Kouji Senzaki, Takashi Shiga. Contribution of the Runx1 transcription factor to axonal pathfinding and muscle innervation by hypoglossal motoneurons. Developmental Neurobiology 75 (11), 1295-1314, 2015.(神経科学)
    https://tsukuba.repo.nii.ac.jp/?action=pages_view_main&active_action=repository_view_main_item_detail&item_id=36404&item_no=1&page_id=13&block_id=83
  11. Tomoyuki Masuda*, Chie Sakuma, Hiroyuki Yaginuma, Masahiko Taniguchi. Attractive and permissive activities of semaphorin 5A toward dorsal root ganglion axons in higher vertebrate embryos. Cell Adhesion and Migration 8 (6), 603-606, 2014.(神経科学・軸索誘導)
    https://www.tandfonline.com/doi/full/10.4161/19336918.2014.972770
  12. Takashi Namba, Yuji Kibe, Yasuhiro Funahashi, Shinichi Nakamuta, Tetsuya Takano, Takuji Ueno, Akiko Shimada, Sachi Kozawa, Mayumi Okamoto, Yasushi Shimoda, Kanako Oda, Yoshino Wada, Tomoyuki Masuda, Akira Sakakibara, Michihiro Igarashi, Takaki Miyata, Catherine Faivre-Sarrailh, Kosei Takeuchi, Kozo Kaibuchi*. Pioneering axons regulate neuronal polarization in the developing cerebral cortex. Neuron 81 (4), 814-829, 2014.(神経科学)
    https://www.sciencedirect.com/science/article/pii/S089662731301146X?via%3Dihub
  13. Tomoyuki Masuda*, Chie Sakuma, Atsuko Nagaoka, Toshiyuki Yamagishi, Shuichi Ueda, Takahiro Nagase, Hiroyuki Yaginuma. Follistatin-like 5 (Fstl5) is expressed in restricted areas of the adult mouse brain: Implications for its function in the olfactory system. Congenital Anomalies 54 (1), 63-66, 2014.(組織学・神経科学)
    https://tsukuba.repo.nii.ac.jp/?action=pages_view_main&active_action=repository_view_main_item_detail&item_id=46013&item_no=1&page_id=13&block_id=83
  14. Tomoyuki Masuda*, Chie Sakuma, Takayuki Ueno, Yuriko Yamada, Hideki Ohmomo, Shuichi Ueda, Toshiyuki Yamagishi, Hiroyuki Yaginuma. Spatiotemporal patterns of the Huntingtin-interacting protein 1-related (Hip1r) gene in the mouse head. Congenital Anomalies 53 (4), 141-148, 2013.(組織学・神経変性疾患)
    https://onlinelibrary.wiley.com/doi/abs/10.1111/cga.12023
  15. Tomoyuki Masuda*, Masahiko Taniguchi, Chie Sakuma, Toshiyuki Yamagishi, Shuichi Ueda, Masahumi Kawaguchi, Hiroyuki Yaginuma. Development of the dorsal ramus of the spinal nerve in the mouse embryo: Involvement of semaphorin 3A in dorsal muscle innervation. Congenital Anomalies 53 (3), 122-126, 2013.(神経科学・軸索誘導)
    https://onlinelibrary.wiley.com/doi/abs/10.1111/cga.12019
  16. Nobumi Kobayashi, Shunsaku Homma, Tomoaki Okada, Tomoyuki Masuda, Noboru Sato, Keiji Nishiyama, Chie Sakuma, Takako Shimada, Hiroyuki Yaginuma*. Elucidation of target muscle and detailed development of dorsal motor neurons in chick spinal cord. Journal of Comparative Neurology 521 (13), 2987-3002, 2013.(神経科学・神経解剖学)
    https://onlinelibrary.wiley.com/doi/abs/10.1002/cne.23326
  17. Masaaki Yoshikawa, Yuuki Murakami, Kouji Senzaki, Tomoyuki Masuda, Shigeru Ozaki, Yoshiaki Ito, Takashi Shiga. Co-expression of Runx1 and Runx3 in mechanoreceptive dorsal root ganglion neurons. Developmental Neurobiology 73 (6), 469-479, 2013.(神経科学)
    https://onlinelibrary.wiley.com/doi/abs/10.1002/dneu.22073
  18. Tomoyuki Masuda*, Chie Sakuma, Masahiko Taniguchi, Ayae Kanemoto, Madoka Yoshizawa, Kaishi Satomi, Hideaki Tanaka, Kosei Takeuchi, Shuichi Ueda, Hiroyuki Yaginuma, Takashi Shiga. Development of the dorsal ramus of the spinal nerve in the chick embryo: A close relationship between development and expression of guidance cues. Brain Research 1480, 30-40, 2012.(神経科学・軸索誘導)
    https://www.sciencedirect.com/science/article/pii/S0006899312014291?via%3Dihub
  19. Tomoyuki Masuda*, Chie Sakuma, Toshiyuki Yamagishi, Takayuki Ueno, Yuriko Yamada, Hiroyuki Yaginuma. Molecular cloning and expression pattern of the splicing variant of chick neuron navigator 2. Saito Ho-on Kai Museum of Natural History Research Bulletin (斎藤報恩会自然史博物館) 75, 7-17, 2011.(組織学・神経科学)
    https://tsukuba.repo.nii.ac.jp/?action=pages_view_main&active_action=repository_view_main_item_detail&item_id=44531&item_no=1&page_id=13&block_id=83
  20. Kenta Kobayashi, Tomoyuki Masuda, Masanori Takahashi, Jun-ichi Miyazaki, Masahiro Nakagawa, Motokazu Uchigashima, Masahiko Watanabe, Hiroyuki Yaginuma, Noriko Osumi, Kozo Kaibuchi, Kazuto Kobayashi. Rho/Rho-kinase signaling pathway controls axon patterning of a specified subset of cranial motor neurons. European Journal of Neuroscience 33 (4), 612-621, 2011.(神経科学・軸索伸長)
    https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1460-9568.2010.07554.x
  21. Masahiko Taniguchi, Tomoyuki Masuda, Yoshinori Mikami, Masafumi Kimura, Tomoyuki Yoshida, Masayoshi Mishina, Takao Shimizu. Identification and characterization of a novel zebrafish semaphorin. Neuroscience Letters 488 (1), 215-220, 2011.(神経科学・分子生物学)
    https://www.sciencedirect.com/science/article/pii/S0304394010014862?via%3Dihub
  22. Tomoyuki Masuda*, Chie Sakuma, Kenta Kobayashi, Kazufumi Kikuchi, Emi Soda, Takashi Shiga, Kazuto Kobayashi, Hiroyuki Yaginuma. Laminin peptide YIGSR and its receptor regulate sensory axonal response to the chemoattractive guidance cue in the chick embryo. Journal of Neuroscience Research 87 (2), 353-359, 2009.(神経科学・軸索誘導)
    https://onlinelibrary.wiley.com/doi/abs/10.1002/jnr.21868
  23. Tomoyuki Masuda*, Nobuyuki Kai, Chie Sakuma, Kazuto Kobayashi, Hisashi Koga, Hiroyuki Yaginuma. Laser capture microdissection and cDNA analysis for identification of mouse KIAA/FLJ genes differentially expressed in the embryonic dorsal spinal cord. Brain Research 1249, 61-67, 2009.(神経科学・マイクロアレイ)
    https://www.sciencedirect.com/science/article/pii/S0006899308025183?via%3Dihub
  24. Tomoyuki Masuda*†, Keisuke Watanabe†, Chie Sakuma†, Kazuhiro Ikenaka, Katsuhiko Ono, Hiroyuki Yaginuma. Netrin-1 acts as a repulsive guidance cue for sensory axonal projection toward the spinal cord. The Journal of Neuroscience 28 (41), 10380-10385, 2008.(神経科学・軸索誘導)
    http://www.jneurosci.org/content/28/41/10380
  25. Masafumi Kimura†, Masahiko Taniguchi*†, Yoshinori Mikami, Tomoyuki Masuda, Tomoyuki Yoshida, Masayoshi Mishina, Takao Shimizu. Identification and characterization of zebrafish semaphorin 6D. Biochemical and Biophysical Research Communications 363 (3), 762-768, 2007.(神経科学・分子生物学)
    https://www.sciencedirect.com/science/article/pii/S0006291X07020025?via%3Dihub
  26. Tomoyuki Masuda*†, Chie Sakuma†, Masahiko Taniguchi, Kenta Kobayashi, Kazuto Kobayashi, Takashi Shiga, Hiroyuki Yaginuma. Guidance cues from the embryonic dorsal spinal cord chemoattract dorsal root ganglion axons. Neuroreport 18 (16), 1645-1649, 2007.(神経科学・軸索誘導)
    https://insights.ovid.com/crossref?an=00001756-200710290-00003
  27. Masahiko Taniguchi*, Tomoyuki Masuda, Masahiro Fukaya, Hirotaka Kataoka, Masami Mishina, Hiroyuki Yaginuma, Masahiko Watanabe, Takao Shimizu. Identification and characteraization of a novel member of murine semaphorin family. Genes to Cells 10, 785-792, 2005.(神経科学・分子生物学)
    https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1365-2443.2005.00877.x
  28. Tomoyuki Masuda, Fumihiko Fukamauchi, Yasuo Takeda, Hajime Fujisawa, Kazutada Watanabe, Nobuo Okado, Takashi Shiga. Developmental regulation of notochord-derived repulsion for dorsal root ganglion axons. Molecular and Cellular Neuroscience 25 (2), 217-227, 2004.(神経科学・軸索誘導)
    https://www.sciencedirect.com/science/article/pii/S1044743103003257?via%3Dihub
  29. Tomoyuki Masuda, Hiroshi Tsuji, Masahiko Taniguchi, Takeshi Yagi, Marc Tessier-Lavigne, Hajime Fujisawa, Nobuo Okado, Takashi Shiga. Differential non-target-derived repulsive signals play a critical role in shaping initial axonal growth of dorsal root ganglion neurons. Developmental Biology 254 (2), 289-302, 2003.(神経科学・軸索誘導)
    https://www.sciencedirect.com/science/article/pii/S0012160602000878?via%3Dihub
  30. Ken-ichi Inoue†, Shigeru Ozaki†, Takashi Shiga, Kosei Ito, Tomoyuki Masuda, Nobuo Okado, Tsutomu Iseda, Saburo Kawaguchi, Masaharu Ogawa, Suk-Chul Bae, Namiko Yamashita, Shigeyoshi Itohara, Norio Kudo, Yoshiaki Ito*. Runx3 controls the axonal projection of proprioceptive dorsal root ganglion neurons. Nature Neuroscience 5 (10), 946-954, 2002.(神経科学)
    http://www.nature.com/articles/nn925
  31. Takashi Shiga, Kikuyo Inoue, Tomoyuki Masuda. Differential expression of the islet-1 homeodomain protein in the limb bud of the chick embryo. Anatomy and Embryology (現 Brain Structure and Function) 205 (3), 223-228, 2002.(細胞生物学)
    https://link.springer.com/article/10.1007%2Fs00429-002-0238-9
  32. Tomoyuki Masuda, Nobuo Okado, Takashi Shiga. The involvement of axonin-1/SC2 in mediating the notochord-derived chemorepulsive activities for dorsal root ganglion neurites. Developmental Biology 224 (2), 112-121, 2000.(神経科学・軸索誘導)
    https://www.sciencedirect.com/science/article/pii/S0012160600998130?via%3Dihub

 

英語総説など  (* corresponding author)

  1. Tomoyuki Masuda*. Contactin-2/TAG-1, active on the front line for three decades. Cell Adhesion and Migration 11 (5-6), 524-531, 2017.(神経科学・細胞接着分子)
    https://www.tandfonline.com/doi/full/10.1080/19336918.2016.1269998
  2. Tomoyuki Masuda*, Masahiko Taniguchi*. Contribution of semaphorins to the formation of the peripheral nervous system in higher vertebrates. Cell Adhesion and Migration 10 (6), 593-603, 2016.(神経科学)
    https://www.tandfonline.com/doi/full/10.1080/19336918.2016.1243644
  3. Tomoyuki Masuda*, Masahiko Taniguchi. Congenital diseases and semaphorin signaling: Overview to date of the evidence linking them. Congenital Anomalies 55 (1), 26-30, 2015.(神経科学・先天異常)
    https://onlinelibrary.wiley.com/doi/abs/10.1111/cga.12095
  4. Tomoyuki Masuda*, Hiroyuki Yaginuma. Formation of peripheral nerve pathways by chemorepulsive and chemoattractive cues with special reference to innervation of the dorsal ramus. In “Recent Research Developments in Neurochemistry, Vol. 8,” Pandalai, S.G. (Ed), Research Signpost, India, pp. 11-18. 2014. ISBN: 978-8130805429.(神経科学・軸索誘導)
  5. Shuichi Ueda*, Kenichi Inoue, Ayuka Ehara, Tomoyuki Masuda, Shin-Ichi Sakakibara, Kanji Yoshimoto. Neuroprotective effects of melatonin in the nigrostriatal and mesolimbic dopaminergic systems in the Zitter rat. In “Melatonin: Therapeutic value and Neuroprotection,” Venkataramanujam Srinivasan, Gabriella Gobbi, Samuel D Shillcutt, Sibel Suzen (Eds), CRC press, Taylor &Francis Group, Florida, USA, pp. 179-188. 2014. ISBN-10: 1482220091. ISBN-13: 978-1482220094.(神経科学・メラトニン)
  6. Tomoyuki Masuda*, Takashi Shiga, Hiroyuki Yaginuma. Sensory axonal guidance by chemorepulsive and chemoattractive cues in the higher vertebrates. In “Axons: Cell Biology, Molecular Dynamics and Roles in Neural Repair and Rehabilitation,” Yamamoto, H., Oshiro, A. (Eds), Nova Science Publishers, Inc., New York, USA, pp. 335-339, 2013. ISBN-10: 1629480517. ISBN-13: 978-1629480510.(神経科学・軸索誘導) 
  7. Tomoyuki Masuda*, Takashi Shiga, Hiroyuki Yaginuma, Shuichi Ueda. Laminins as a modulator of the axonal response to guidance cues. In “Laminins: Structure, Biological Activity and Role in Disease,” Adams, DC., Garcia, EO. (Eds), Nova Science Publishers, Inc., New York, USA, pp. 131-135, 2013. ISBN-10: 1626185689. ISBN-13: 978-1626185685.(神経科学・軸索誘導)
  8. Tomoyuki Masuda*, Chie Sakuma, Hiroyuki Yaginuma. Role for netrin-1 in sensory axonal guidance in higher vertebrates. Fukushima Journal of Medical Science 55 (1), 1-6, 2009.(神経科学・軸索誘導)
    https://www.jstage.jst.go.jp/article/fms/55/1/55_1/_article
  9. Tomoyuki Masuda*, Hiroyuki Yaginuma, Chie Sakuma, Katsuhiko Ono. Netrin-1 signaling for sensory axons: involvement in sensory axonal development and regeneration. Cell Adhesion and Migration 3 (2), 171-173, 2009.(神経科学・神経再生)
    https://www.tandfonline.com/doi/abs/10.4161/cam.3.2.7837
  10. Tomoyuki Masuda*, Takashi Shiga. Roles of chondroitin sulfate proteoglycans in the formation of axonal trajectories of dorsal root ganglion neurons. In “Neural Proteoglycans,” Maeda, N. (Ed), Research Signpost, India, pp. 127-137, 2007. ISBN: 8130801434.(神経科学・軸索誘導)
  11. Tomoyuki Masuda, Takashi Shiga. Chemorepulsion and cell adhesion molecules in patterning initial trajectories of sensory axons. Neuroscience Research 51 (4), 337-347, 2005.(神経科学・軸索誘導)
    https://www.sciencedirect.com/science/article/pii/S0168010205000076?via%3Dihub

 

邦文総説など  (* 責任著者)

  1. 増田知之*.TAG-1.脳科学辞典 2016.(神経科学・細胞接着分子)
    https://bsd.neuroinf.jp/wiki/TAG-1
  2. 増田知之*(分担執筆).生物学辞典(脳・神経の項目担当),東京化学同人社,2010. ISBN-10: 4807907352. ISBN-13: 978-4807907359.(神経科学・生物学)
  3. 増田知之*.遺伝子の森でのお宝探し.内藤財団時報 86, 81, 2010. ISSN: 0911-971X.(その他)
    https://www.naito-f.or.jp/jiho/pdf/86/86_036.pdf#search=%27%E5%A2%97%E7%94%B0%E7%9F%A5%E4%B9%8B+%E3%81%8A%E5%AE%9D%E6%8E%A2%E3%81%97%27
  4. Tomoyuki Masuda*, Chie Sakuma, Hiroyuki Yaginuma. Molecular mechanisms of patterning initial trajectories of sensory neurons. Saishin Igaku 64 (4), 938-943, 2009. ISSN 0370-8241.(神経科学・軸索誘導)
  5. 増田知之*.感覚神経ネットワークを形成する分子メカニズム.福島医学雑誌 59 (1), 41-42, 2009. ISSN: 0016-2582.(神経科学・軸索誘導)
  6. 増田知之*.脊髄一次求心性線維の投射路を形成する分子メカニズム.ブレインサイエンス・レビュー2008(伊藤正男・川合述史 編),クバプロ,東京,pp. 157-180, 2008. ISBN-10: 4878050926. ISBN-13: 978-4878050923.(神経科学・軸索誘導)

 

特許申請

  1. (米国特許商標局)軸索の伸長又は誘引促進剤及びその使用,AXON ATTRACTANT OR GROWTH PROMOTER, AND METHOD USING THE SAME. 発明者(国立大学法人筑波大学・増田知之),出願人(国立大学法人筑波大学),U.S. Provisional Application: 62/061,707(出願番号:US 62/061, 707). 出願日2014年10月9日.
  2. 感覚性の末梢神経線維の伸長又は誘引促進剤,神経疾患又は損傷の治療剤及び足場デバイス.発明者(国立大学法人筑波大学・増田知之),出願人(国立大学法人 筑波大学),出願番号:特願2015-200550,出願日2015年10月8日,公開番号(文献番号):特開2016-079176,公開日 2016年5月16日.

 

特許取得

  1. 感覚性の末梢神経線維の伸長又は誘引促進剤.発明者(国立大学法人筑波大学・増田知之,石井一弘),出願人(国立大学法人 筑波大学),特許番号:特許第6278524号,登録日2018年1月26日